The Premier League kicks off this weekend as Liverpool, last season's runners-up, open the campaign on Friday against Norwich 8:00pm, with City at West Ham on Saturday 12:30pm.
Several new laws, plus video assistant referees, have been introduced to England's top flight this season.
Eleven of the 20 clubs broke their transfer record, while there have been three new managerial appointments.
Domestic treble winners City, who have picked up 198 points in the past two seasons, are bidding to become the first team to win three Premier League titles in a row since Manchester United's hat-trick of titles from 2007 to 2009.
European champions Liverpool, who earned 97 points last season – a record high for runners-up in any of Europe's top five leagues – are tipped to be their main rivals again.
Tottenham, Chelsea, Manchester United and Arsenal are the other teams expected to be battling for Champions League places.